Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81851-y
Abstract: Cell transmembrane receptors and extracellular matrix components play a pivotal role in regulating cell activity and providing for the concerted integration of cells in the tissue structures. We have assessed DNA methylation in the promoter… read more here.
Keywords: promoter hypermethylation; promoter; hypermethylation; abnormal promoter ... See more keywords
Recognition of Tumor Nidogen-1 by Neutrophil C-Type Lectin Receptors
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10040908
Abstract: Neutrophil-mediated cytotoxicity toward tumor cells requires cell contact and is mediated by hydrogen peroxide. We have recently shown that Cathepsin G expressed on the neutrophil surface interacts with tumor RAGE, and this interaction facilitates neutrophil… read more here.
Keywords: cytotoxicity; tumor cells; nidogen; recognition tumor ... See more keywords