Pharmacokinetics and Bioequivalence of 2 Nifedipine Controlled-Release Tablets: A Randomized, Single-Dose, 2-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1258
Abstract: The aim of this study was to evaluate the bioequivalence of generic nifedipine controlled-release tablet compared to branded product under fasting and fed conditions. A randomized, single-dose, 2-period, crossover study with a 7-day washout period… read more here.
Keywords: fasting fed; period; nifedipine; concentration ... See more keywords
Dual effect of nifedipine on pregnant human myometrium contractility: Implication of TRPC1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30666
Abstract: Nifedipine, an L‐type voltage‐gated Ca2+ channel (L‐VGCC) blocker, is one of the most used tocolytics to treat preterm labor. In clinical practice, nifedipine efficiently decreases uterine contractions, but its efficacy is limited over time, and… read more here.
Keywords: pregnant human; implication trpc1; effect; nifedipine ... See more keywords
Effect of transradial catheterization and nifedipine on flow- and nitroglycerin-mediated dilations of distal and proximal radial artery
Sign Up to like & getrecommendations! Published in 2022 at "Coronary Artery Disease"
DOI: 10.1097/mca.0000000000001193
Abstract: Objective Radial artery (RA) dysfunction after transradial access intervention is not limited to the distal portion but can also occur in the proximal portion of RA. The aim of the present study was to assess… read more here.
Keywords: nifedipine; effect; nitroglycerin mediated; distal proximal ... See more keywords
Fetal echocardiographic evaluation before and after nifedipine treatment in preterm labor
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DOI: 10.1111/echo.15444
Abstract: To assess the effect of nifedipine used for tocolysis on cardiac morphology and functions. read more here.
Keywords: fetal echocardiographic; nifedipine; echocardiographic evaluation; treatment preterm ... See more keywords
Oral nifedipine and phytosterol, intravenous nicardipine, and oral nifedipine only: Three-arm, retrospective, cohort study for management of severe preeclampsia
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DOI: 10.1515/biol-2022-0581
Abstract: Abstract The treatment of preeclampsia is delivering women and extracting the placenta, but the Chinese Society of Obstetrics and Gynecology guidelines do not recommend the delivery of babies without severe features. The objectives of the… read more here.
Keywords: nifedipine; phytosterol; cohort; oral nifedipine ... See more keywords
A HPLC-MS/MS METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS DETERMINATION OF NIFEDIPINE AND ENALAPRIL IN HUMAN PLASMA
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DOI: 10.22159/ijap.2018v10i4.24528
Abstract: Objective: The main purpose of this study was to develop a simple, precise, rapid and accurate method for the simultaneous quantification of nifedipine and enalapril in human plasma. Methods: Chromatography was achieved on Discovery C18,… read more here.
Keywords: human plasma; method; enalapril; enalapril human ... See more keywords
Vitamin D Enhances Efficacy of Oral Nifedipine in Treating Preeclampsia with Severe Features: A Double Blinded, Placebo-Controlled and Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00865
Abstract: Vitamin D (VD) has exhibited immunomodulatory role in the pathogenesis of preeclampsia. We hypothesize VD potentiate nifedipine treatment for preeclampsia by shortened the time to control blood pressure and prolong time before subsequent hypertensive crisis.… read more here.
Keywords: control; time; preeclampsia; nifedipine ... See more keywords
Nifedipine Ameliorates Cellular Differentiation Defects of Smn-Deficient Motor Neurons and Enhances Neuromuscular Transmission in SMA Mice
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DOI: 10.3390/ijms24087648
Abstract: In spinal muscular atrophy (SMA), mutations in or loss of the Survival Motor Neuron 1 (SMN1) gene reduce full-length SMN protein levels, which leads to the degeneration of a percentage of motor neurons. In mouse… read more here.
Keywords: motor neurons; motor; sma mice; nifedipine ... See more keywords
Study of supramolecular complex of nifedipine with arabinogalactan on Wistar and ISIAH rats.
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic delivery"
DOI: 10.4155/tde-2020-0115
Abstract: Aim: Physicochemical and pharmacological study of the supramolecular inclusion complexes of the hypotensive drug nifedipine (NF) with the larch polysaccharide arabinogalactan (AG). Materials & methods: The NF:AG complexes were obtained and their physicochemical properties were… read more here.
Keywords: study supramolecular; supramolecular complex; complex nifedipine; nifedipine arabinogalactan ... See more keywords