Acute and subchronic PCP attenuate D2 autoreceptor signaling in substantia nigra dopamine neurons
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2019.01.108
Abstract: Phencyclidine (PCP) administration is commonly used to model schizophrenia in laboratory animals. While PCP is well-characterized as an antagonist of glutamate-sensitive N-methyl-D-aspartate (NMDA) receptors, its effects on dopamine signaling are not well understood. Here we… read more here.
Keywords: autoreceptor; nigra dopamine; dopamine; substantia nigra ... See more keywords