Articles with "nigrostriatal synucleinopathy" as a keyword



STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2118819119

Abstract: Significance It is increasingly recognized that chronic neuroinflammation is causally relevant to neurodegeneration. In Parkinson’s disease (PD), α-synuclein pathology activates inflammatory signaling that disturbs parenchymal homeostasis and disrupts neuron-glia interactions. Herein, we report that the… read more here.

Keywords: sting mediates; neuroinflammation nigrostriatal; neuroinflammation; nigrostriatal synucleinopathy ... See more keywords