Thioether-Directed NiH-Catalyzed Remote γ-C(sp3)-H Hydroamidation of Alkenes by 1,4,2-Dioxazol-5-ones.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c05834
Abstract: A NiH-catalyzed thioether-directed cyclometalation strategy is developed to enable remote methylene C-H bond amidation of unactivated alkenes. Due to the preference for five-membered nickelacycle formation, the chain-walking isomerization initiated by the NiH insertion to an… read more here.
Keywords: directed nih; remote sp3; catalyzed remote; thioether directed ... See more keywords
NiH-catalyzed dearomative hydroalkylation of indoles.
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DOI: 10.1039/d2cc01650h
Abstract: A NiH-catalyzed intermolecular dearomative hydroalkylation of indoles has been developed, which assembles an array of structurally diverse C2-alkylated indolines with moderate to excellent yields. This protocol exhibits good functional group tolerance, allowing for late-stage functionalization… read more here.
Keywords: hydroalkylation indoles; catalyzed dearomative; nih catalyzed; dearomative hydroalkylation ... See more keywords
NiH-catalyzed C(sp3)-Si coupling of alkenes with vinyl chlorosilanes.
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DOI: 10.1039/d2cc04232k
Abstract: A novel NiH-catalyzed highly regioselective coupling of alkenes with vinyl chlorosilanes, constructing C-Si bonds, is developed. Under mild reaction conditions, a series of benzyl organosilanes with various functional groups could be accessed. Further synthetic studies… read more here.
Keywords: alkenes vinyl; sp3 coupling; vinyl chlorosilanes; nih catalyzed ... See more keywords