Triphenylamine‐Substituted Nile Red Derivatives with Efficient Reactive Oxygen Species Generation for Robust and Broad‐Spectrum Antimicrobial Photodynamic Therapy and Abscess Wound Healing
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202421072
Abstract: Infections caused by drug‐resistant bacteria represent a major contributor to high mortality rates, underscoring the urgent need for effective non‐antibiotic drugs and alternative therapies. Antimicrobial photodynamic therapy (aPDT) emerges as an innovative treatment due to… read more here.
Keywords: red derivatives; antimicrobial photodynamic; wound healing; nile red ... See more keywords
Nile Red quantifier: A novel and quantitative tool to study lipid accumulation in patient-derived circulating monocytes using confocal microscopy.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.06.463
Abstract: s / Atherosclerosis 263 (2017) e111ee282 e146 (79.82±15.25% vs. 74.51±5.87%;p1⁄40.274 for fibrotic and 2.83±2.60% vs. 2.40±1.58%;p1⁄40.617 for calcific tissue). Both patient groups had similar plaque necrolipidic tissue content (17.8±13.49% vs. 23.10±5.35%;p1⁄40.219 in prediabetic vs. diabetic… read more here.
Keywords: medicine; microscopy; nile red; tissue ... See more keywords
Exploring the potential of photoluminescence spectroscopy in combination with Nile Red staining for microplastic detection.
Sign Up to like & getrecommendations! Published in 2020 at "Marine pollution bulletin"
DOI: 10.1016/j.marpolbul.2020.111475
Abstract: The significant amount of plastic litter in the form of microplastics (size read more here.
Keywords: detection; nile red; photoluminescence spectroscopy; spectroscopy ... See more keywords
Nile Red staining for detecting microplastics in biota: Preliminary evidence.
Sign Up to like & getrecommendations! Published in 2021 at "Marine pollution bulletin"
DOI: 10.1016/j.marpolbul.2021.112888
Abstract: Nile Red is a lipophilic, metachromatic and solvatochromic dye used as an alternative or complementary method to aid identification of microplastics in routine analysis of biological samples. It was rarely used in biota since organic… read more here.
Keywords: detecting microplastics; staining detecting; nile red; microplastics biota ... See more keywords
Nile Red fluorescence spectrum decomposition enables rapid screening of large protein aggregates in complex biopharmaceutical formulations like influenza vaccines.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.04.066
Abstract: The extensive presence of large (high molecular weight) protein aggregates in biopharmaceutical formulations is a concern for formulation stability and possibly safety. Tests to screen large aggregate content in such bioformulations are therefore needed for… read more here.
Keywords: fluorescence; nile red; biopharmaceutical formulations; protein aggregates ... See more keywords
Fluorescent Antimicrobial Peptides Based on Nile Red: Effect of Conjugation Site and Chemistry on Wash-Free Staining of Bacteria.
Sign Up to like & getrecommendations! Published in 2024 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.4c00331
Abstract: Fluorescent probes for bacterial detection can be obtained by conjugating antimicrobial peptides with fluorescent dyes. However, little is known about the effect of the conjugation site and linker chemistry on staining efficiency. We synthesized three… read more here.
Keywords: chemistry; conjugation site; site; nile red ... See more keywords
Exploring the Photodynamics of a New 2D-MOF Composite: Nile Red@Al–ITQ-HB
Sign Up to like & getrecommendations! Published in 2018 at "ACS Omega"
DOI: 10.1021/acsomega.7b01718
Abstract: In this work, we unravel the photodynamics of Nile Red (NR) interacting with Al–ITQ-HB nanostructure, a new layer-type metal–organic framework (MOF) with potential catalytic and photonic applications. Steady-state spectroscopy reveals the presence of NR monomers… read more here.
Keywords: new mof; exploring photodynamics; nile red; itq ... See more keywords
Ratiometric fluorescence nanoscopy and lifetime imaging of novel Nile Red analogs for analysis of membrane packing in living cells
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-64180-8
Abstract: Subcellular membranes have complex lipid and protein compositions, which give rise to organelle-specific membrane packing, fluidity, and permeability. Due to its exquisite solvent sensitivity, the lipophilic fluorescence dye Nile Red has been used extensively to… read more here.
Keywords: fluorescence; membrane packing; nile red; living cells ... See more keywords
Amphipathic helical peptide-Nile red probes for fluorescence probing of the lipid packing defects and their surrounding membranes on exosomes
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-08534-w
Abstract: Amphipathic helical (AH) peptide-based fluorescent probes were explored for analysis of lipid packing defects (LPDs) in the membrane surface of exosomes. Two kinds of AH peptide sequences, derived from the C-terminal sequence of Apolipoprotein A-I… read more here.
Keywords: amphipathic helical; packing defects; lipid packing; helical peptide ... See more keywords
Derivatizing Nile Red fluorophores to quantify the heterogeneous polarity upon protein aggregation in the cell.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00629d
Abstract: Protein aggregation in the cell is often manifested by the formation of subcellular punctate structures. Herein, we modulated the solvatochromism and solubility of Nile Red fluorophore derivatives to quantitatively study the polarity inside pathogenic protein… read more here.
Keywords: aggregation cell; nile red; protein aggregation; polarity ... See more keywords
Nile Red derivatives enable improved ratiometric imaging for nerve-specific contrast
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.23.7.076002
Abstract: Abstract. Surgical nerve damage due to difficulty with identification remains a major risk for postsurgical complications and decreased quality of life. Fluorescence-guided surgery offers a means to specifically highlight tissues of interest such as nerves… read more here.
Keywords: ratiometric imaging; nile red; nerve specific; nerve ... See more keywords