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Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line

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Published in 2019 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2018.1549075

Abstract: Abstract The aim of this work is development of a nontoxic, long-term stable solid lipid nanoparticles (SLN) formulation for the loading of Nimesulide (NiM) by a 22 factorial design. The optimized formulation was composed of… read more here.

Keywords: factorial design; sln; lipid nanoparticles; nim sln ... See more keywords