Kinetically Controllable Construction of Nine-Membered Carbocycles via Pd-Catalyzed Decarboxylative Cycloaddition.
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DOI: 10.1021/acs.orglett.2c00808
Abstract: A kinetically controllable strategy toward the construction of otherwise challenging nine-membered carbocycles is reported. This Pd-catalyzed decarboxylative procedure utilizes vinyl methylene cyclic carbonates as the C5-dipole and allylidenemalononitriles as C4-building blocks. The protocol features user-friendly… read more here.
Keywords: kinetically controllable; nine membered; membered carbocycles; controllable construction ... See more keywords
Hydride Transfer-Initiated Cross-Dehydrogenative Coupling Reaction to Access Nine-Membered Rings.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00193
Abstract: An unprecedented hydride transfer-triggered cross-dehydrogenative coupling of two C(sp3)-H bonds to target nine-membered rings has been developed. Salient features of this methodology include atom and step economy and metal-free and redox-neutral conditions, with water as… read more here.
Keywords: nine membered; membered rings; hydride transfer; dehydrogenative coupling ... See more keywords