Zwitterionic AIEgens: Rational Molecular Design for NIR‐II Fluorescence Imaging‐Guided Synergistic Phototherapy
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202007026
Abstract: Fluorescence imaging in the second near‐infrared region (NIR‐II) can penetrate tissue at centimeter depths and obtain high image fidelity. However, facile synthesis of small‐molecule fluorescent photosensitizers for efficient NIR‐II fluorescence imaging as well as photodynamic… read more here.
Keywords: fluorescence; fluorescence imaging; imaging guided; synergistic phototherapy ... See more keywords
Precise Deciphering of Brain Vasculatures and Microscopic Tumors with Dual NIR-II Fluorescence and Photoacoustic Imaging.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201902504
Abstract: Diagnostics of cerebrovascular structures and microscopic tumors with intact blood-brain barrier (BBB) significantly contributes to timely treatment of patients bearing neurological diseases. Dual NIR-II fluorescence and photoacoustic imaging (PAI) is expected to offer powerful strength,… read more here.
Keywords: microscopic tumors; fluorescence photoacoustic; nir fluorescence; dual nir ... See more keywords
Self‐Sacrificially Degradable Pseudo‐Semiconducting Polymer Nanoparticles that Integrate NIR‐II Fluorescence Bioimaging, Photodynamic Immunotherapy, and Photo‐Activated Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203820
Abstract: Semiconducting polymers (SP) hold great promise for cancer phototherapy due to their excellent optical properties; however, their clinical application is still hampered by their poor biodegradability. Herein, a self‐sacrificially biodegradable pseudo‐semiconducting polymer (PSP) for NIR‐II… read more here.
Keywords: self sacrificially; nir fluorescence; photodynamic immunotherapy; psp ... See more keywords
Self‐Assembled Ag2S‐QD Vesicles for In Situ Responsive NIR‐II Fluorescence Imaging‐Guided Photothermal Cancer Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Optical Materials"
DOI: 10.1002/adom.202100233
Abstract: Bioimaging guided photothermal therapy possesses great promise for lesion diagnosis and effective treatment. However, distinguishing lesion from normal tissues for precise cancer therapy remains a great challenge. Herein, a stimulation‐responsive assembled Ag2S vesicle (Ag2S Ve)… read more here.
Keywords: fluorescence; therapy; nir fluorescence; guided photothermal ... See more keywords
Rational Molecular Engineering of Organic Semiconducting Nanoplatforms for Advancing NIR‐II Fluorescence Theranostics
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Optical Materials"
DOI: 10.1002/adom.202201067
Abstract: Second near‐infrared window (NIR‐II, 1000−1700 nm) fluorescence imaging (FI) in phototheranostics benefits from deep tissue penetration, negligible body spontaneous fluorescence, exceptional spatiotemporal resolution, and diversified imaging agents. Inorganic and metal nanomaterials with NIR‐II emission are… read more here.
Keywords: rational molecular; semiconducting nanoplatforms; nir fluorescence; organic semiconducting ... See more keywords
Lutetium‐Based Nanoprobes for Radiosensitization with Immune Microenvironment Remodeling and NIR‐II Fluorescence Imaging‐Guided Surgery in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202510136
Abstract: Colorectal cancer (CRC) is among the top five leading cancers worldwide. Preoperative concurrent chemoradiotherapy is recommended for locally advanced CRC. Radiotherapy (RT), a traditional cancer treatment, not only controls local tumor growth but also potentially… read more here.
Keywords: colorectal cancer; cancer; nir fluorescence; crc ... See more keywords
NIR‐II Fluorescence Imaging‐guided Photothermal Activated Pyroptosis For Precision Therapy Of Glioma
Sign Up to like & getrecommendations! Published in 2025 at "ChemBioChem"
DOI: 10.1002/cbic.202400804
Abstract: The resistance of cancer cells to apoptosis poses a significant challenge in cancer therapy, driving the exploration of alternative cell death pathways such as pyroptosis, known for its rapid and potent effects. While initial efforts… read more here.
Keywords: therapy; pyroptosis; nir fluorescence; fluorescence imaging ... See more keywords
Aggregation‐Induced Emission Near‐Infrared (NIR)‐II‐Conjugated Polymers Coupled With Nonconjugated Segments for NIR‐II Fluorescence Imaging–Guided NIR‐II Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.202400268
Abstract: The development of conjugated polymer–based water‐soluble nanoparticles for near‐infrared‐II (NIR‐II) fluorescence (FL; 1000–1700 nm)‐guided photothermal therapy holds promise in advancing cancer treatment. However, excessive nonradiative decay leads to almost complete quenching of conjugated polymers’ fluorescence. Therefore,… read more here.
Keywords: conjugated polymers; nir fluorescence; fluorescence; fluorescence imaging ... See more keywords
Recent Advances in Near-Infrared-II Fluorescence Imaging for Deep-Tissue Molecular Analysis and Cancer Diagnosis.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202202035
Abstract: Fluorescence imaging with high sensitivity and minimal invasiveness has received tremendous attention, which can accomplish visualized monitoring and evaluation of cancer progression. Compared with the conventional first near-infrared (NIR-I) optical window (650-950 nm), fluorescence imaging in… read more here.
Keywords: deep tissue; fluorescence imaging; nir fluorescence; cancer ... See more keywords
NIR-II Fluorescence Imaging-Guided Oxygen Self-Sufficient Nano-Platform for Precise Enhanced Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205647
Abstract: Tumor hypoxia and systemic toxicity seriously affect the efficacy of photodynamic therapy (PDT) and are considered as the "Achilles' heel" of PDT. Herein, to combat such limitations, an intelligent orthogonal emissions LDNP@SiO2 -CaO2 and folic… read more here.
Keywords: fluorescence imaging; photodynamic therapy; oxygen; nir fluorescence ... See more keywords
Symmetrically Fluorinated D-π-A Structured Cyanine Dye for Highly Efficient NIR-II Imaging-Guided Cancer Phototheranostics.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202401905
Abstract: Near-infrared-II (NIR-II) fluorescence imaging-guided photothermal therapy (PTT) represents a cutting-edge approach for precise tumor diagnosis and treatment, providing real-time therapeutic efficacy evaluation. However, a significant challenge lies in the creation of phototheranostic agents that provide… read more here.
Keywords: imaging guided; nir fluorescence; fluorescence; tumor ... See more keywords