A Targeted Activatable NIR-IIb Nanoprobe for Highly Sensitive Detection of Ischemic Stroke in a Photothrombotic Stroke Model.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001544
Abstract: Ischemic stroke is a devastating disease resulting in high morbidity and mortality. To date, its early diagnosis still faces challenges. Herein, an efficient detection strategy is proposed, in which a targeted activatable NIR-IIb nanoprobe (V&C/PbS@Ag2… read more here.
Keywords: ischemic stroke; detection; nir iib; targeted activatable ... See more keywords
Brain Tumor Cell Membrane‐Coated Lanthanide‐Doped Nanoparticles for NIR‐IIb Luminescence Imaging and Surgical Navigation of Glioma
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200521
Abstract: Intraoperative visualization of the full extent of brain tumor by luminescence imaging helps to improve the degree and accuracy of brain tumor resection, thereby prolonging the survival of patients. However, the limited imaging depth and… read more here.
Keywords: cell membrane; brain tumor; brain; tumor cell ... See more keywords
High-Specificity In Vivo Tumor Imaging Using Bioorthogonal NIR-IIb Nanoparticles.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202102950
Abstract: Lanthanide-based NIR-IIb nanoprobes are ideal for in vivo imaging. However, existing NIR-IIb nanoprobes often suffer from low tumor-targeting specificity, limiting their widespread use. Here the application of bioorthogonal nanoprobes with high tumor-targeting specificity for in… read more here.
Keywords: nir iib; tumor imaging; specificity vivo; tumor ... See more keywords
Maximum Emission Peak Over 1500 nm of Organic Assembly for Blood–Brain Barrier‐Crossing NIR‐IIb Phototheranostics of Orthotopic Glioblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202208097
Abstract: The development of blood–brain barrier (BBB)‐crossing phototheranostic agents in second near‐infrared window (NIR‐II), especially in the range of 1500–1700 nm (NIR‐IIb), affords great opportunities for glioblastoma (GBM) management. Herein, an organic assembly (denoted as LET‐12)… read more here.
Keywords: iib phototheranostics; blood brain; peak; nir iib ... See more keywords
Targeted Immunoimaging of Tumor-Associated Macrophages in Orthotopic Glioblastoma by the NIR-IIb Nanoprobes.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202202201
Abstract: Developing dynamic and highly sensitive methods for imaging M2-type tumor-associated macrophages (TAMs) is vital for monitoring the tumor progression and assessing the therapeutic efficacy. Here, the fabrication and application of rationally designed Er-based rare-earth nanoprobes… read more here.
Keywords: tumor associated; associated macrophages; tumor; nir iib ... See more keywords
Rational Design of Activatable Lanthanide NIR-IIb Emissive Nanoprobe for In Situ Specific Imaging of HOCl In Vivo.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202400883
Abstract: Hypochlorous acid (HOCl), as an indispensable signaling molecule in organisms, is one of the key members of reactive oxygen species (ROS). However, in vivo, real-time dynamic near-infrared fluorescence imaging of HOCl levels in the 1400-1700 nm… read more here.
Keywords: hocl; nanoprobe; nir iib; imaging hocl ... See more keywords
Advances in Lanthanide‐Based NIR‐IIb Probes for In Vivo Biomedical Imaging
Sign Up to like & getrecommendations! Published in 2024 at "Small Methods"
DOI: 10.1002/smtd.202401462
Abstract: The past decades have witnessed the significant development and practical interest of in vivo biomedical imaging technologies and optical materials in the second‐near infrared (NIR‐II, 1000–1700 nm) window. Imaging with the extended emission wavelength toward… read more here.
Keywords: iib probes; biomedical imaging; nir iib; vivo biomedical ... See more keywords
Visualization of Diabetes Progression by an Activatable NIR-IIb Luminescent Probe.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c02629
Abstract: Developing NIR-IIb luminescence probes with rapid visualization and a high penetration depth is essential for diabetes research. Combining a sensitizing switch with lanthanide-doped nanoparticles (LnNPs) has been employed to fabricate the NIR-IIb probes. However, these… read more here.
Keywords: visualization; nir iib; iib probes; iib ... See more keywords
Visualization of Hypoxic Tumors: Stimulated by NIR-IIb Emissive Erbium(III)-Phthalocyaninate Nanoagent.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c02811
Abstract: This study presents a long-lived NIR-IIb luminogenic nanoagent (ErPc-Sa NPs) based on a newly designed erbium phthalocyaninate complex with impressive quantum yield at 1530 nm (Er, 2.81%) via single molecular self-assembly; NIR-IIb (1500-1700 nm) imaging… read more here.
Keywords: tumors stimulated; nir iib; hypoxic tumors; visualization hypoxic ... See more keywords
A Small-Molecule Based Organic Nanoparticle for Photothermal Therapy and Near-Infrared-IIb Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c11706
Abstract: Near-infrared window IIb (NIR-IIb, 1500-1700 nm) fluorescence imaging demonstrates attractive properties including low scattering, low absorption, and deep tissue penetration, and photothermal therapy (PTT) is also a promising modality for cancer treatment. However, until now,… read more here.
Keywords: near infrared; iib imaging; tqf; tumor ... See more keywords
Carboxyl-Modified Quantum Dots for NIR-IIb Bone Marrow Imaging.
Sign Up to like & getrecommendations! Published in 2024 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c18282
Abstract: Real-time, noninvasive, and nonradiative bone imaging can directly visualize bone health but requires bone-targeted probes with high specificity. Herein, we propose that carboxyl-rich fluorescent nanoprobes are easily absorbed by macrophages in bone marrow during circulation,… read more here.
Keywords: nir iib; bone marrow; marrow imaging; bone ... See more keywords