Inflammatory Microenvironment‐Responsive Nanomotors with NIR Photothermal Effect for Deep Inflammation Elimination and Infection Inhibition
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202416684
Abstract: The infected chronic wound area has a unique microenvironment featuring hypoxia, excessive reactive oxygen species (ROS), and inflammatory conditions. Bacteria‐formed biofilms limit the anti‐inflammation efficiency of most therapeutics by hindering their penetration into deep infected… read more here.
Keywords: microenvironment responsive; nanomotors nir; nir photothermal; inflammation ... See more keywords
Carbon Dot@MXene Nanozymes with Triple Enzyme‐Mimic Activities for Mild NIR‐II Photothermal‐Amplified Nanocatalytic Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202154
Abstract: Nanozymes have shown promising potential in disease treatment owing to the advantages of low‐cost, facile fabrication, and high stability. However, the highly complex tumor microenvironment (TME) and inherent low catalytic activity severely restrict the clinical… read more here.
Keywords: triple enzyme; nir photothermal; enzyme mimic; nanocatalytic therapy ... See more keywords
Degradable Pseudo Conjugated Polymer Nanoparticles with NIR‐II Photothermal Effect and Cationic Quaternary Phosphonium Structural Bacteriostasis for Anti‐Infection Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202200732
Abstract: Photothermal therapy based on conjugated polymers represents a promising antibacterial strategy but still possesses notable limitations. Herein, degradable pseudo conjugated polymers (PCPs) containing photothermal molecular backbones and reactive oxygen species (ROS)‐sensitive thioketal bonds are designed.… read more here.
Keywords: ppcp nps; nir photothermal; effect; therapy ... See more keywords
Metal‐Coordinated NIR‐II Nanoadjuvants with Nanobody Conjugation for Potentiating Immunotherapy by Tumor Metabolism Reprogramming
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202404886
Abstract: Immune checkpoint blockade (ICB) immunotherapy remains hampered by insufficient immunogenicity and a high‐lactate immunosuppressive tumor microenvironment (TME). Herein, a nanobody‐engineered NIR‐II nanoadjuvant with targeting metabolic reprogramming capability is constructed for potentiating NIR‐II photothermal‐ferroptosis immunotherapy. Specifically,… read more here.
Keywords: metabolism; tumor; coordinated nir; nir photothermal ... See more keywords
NIR-II D-A-D-Type Small-Molecule Coordination with Carboxylatopillar[5]Arene: a Multifunctional Phototheranostic for Low-Temperature NIR-II Photothermal/Platinum-Based/Chemodynamic Combination Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "Small"
DOI: 10.1002/smll.202501903
Abstract: Low-temperature second near-infrared region (NIR-II) photothermal therapy (PTT) has shown significant potential in minimizing damage to normal tissues and reducing inflammation. However, it still faces challenge of insufficient immune response. Thus, a multifunctional phototheranostic nanoparticle… read more here.
Keywords: multifunctional phototheranostic; carboxylatopillar arene; platinum based; low temperature ... See more keywords
Enhancing Near-Infrared Photothermal Performance by Molecular Aggregation Optimization in Semiconductive Coordination Polymers.
Sign Up to like & getrecommendations! Published in 2024 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.4c03580
Abstract: Near-infrared (NIR) photothermal conversion materials have recently received widespread attention due to their potential in diverse applications. However, highly efficient organic-based NIR photothermal agents remain limited. Developing strategies to enhance the efficiency of NIR photothermal… read more here.
Keywords: performance molecular; photothermal performance; aggregation; nir photothermal ... See more keywords
Hypoxia-Responsive Thio-Perylene Diimides Delivered via pH-Responsive Polypeptide Nanoparticles: Toward a Combination of NIR Photothermal Therapy and Chemotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.5c19039
Abstract: Developing responsive therapeutic systems based on the tumor microenvironment is crucial for efficient and specific treatments. However, how to achieve sensitive response and efficient anticancer bioactivity remains a challenge. Here, tumor-responsive polypeptide nanoparticles encapsulating thio-perylene… read more here.
Keywords: responsive polypeptide; thio perylene; polypeptide nanoparticles; nir photothermal ... See more keywords
Coupling molecular rigidity and flexibility on fused backbones for NIR-II photothermal conversion†
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc00060h
Abstract: Great attention is being increasingly paid to photothermal conversion in the near-infrared (NIR)-II window (1000–1350 nm), where deeper tissue penetration is favored. To date, only a limited number of organic photothermal polymers and relevant theory… read more here.
Keywords: state; photothermal conversion; nir photothermal; conversion ... See more keywords
Gold-based Nanostructures for Efficient NIR-II Photothermal Conversion: Hybridizing Nanoplates with Solid/Hollow Nanospheres
Sign Up to like & getrecommendations! Published in 2023 at "CrystEngComm"
DOI: 10.1039/d3ce00390f
Abstract: To develop high-efficient near-infrared (NIR) gold (Au)-based photothermal nanomaterials, the architectures of two-dimensional nanoplate/nanosheet or nanoparticles with hollow interiors could be two favorable options to realize the red-shift of the... read more here.
Keywords: nir photothermal; nanostructures efficient; gold based; based nanostructures ... See more keywords
A conjugated molecule based on tetra-fused thienoisoindigo ribbon for NIR-II photothermal cancer therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Chemical communications"
DOI: 10.1039/d5cc01712b
Abstract: Water-soluble nanoparticles (NPs) based on the well-defined 4ThIID molecules, namely 4ThIID NPs, were prepared. Benefiting from the strong NIR-II absorption and high photothermal conversion properties of 4ThIID, the ε1064 × PTCE1064 value of 4ThIID NPs… read more here.
Keywords: conjugated molecule; tetra fused; based tetra; 4thiid nps ... See more keywords
A thermoresponsive nanocomposite integrates NIR-II-absorbing small molecule with lonidamine for pyroptosis-promoted synergistic immunotherapy
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-024-02424-5
Abstract: Photothermal immunotherapy is regarded as the ideal cancer therapeutic modality to against malignant solid tumors; however, its therapeutic benefits are often modest and require improvement. In this study, a thermoresponsive nanoparticle (BTN@LND) composed of a… read more here.
Keywords: pyroptosis; immunotherapy; small molecule; nir photothermal ... See more keywords