Chromosome evolution of Escherichia coli Nissle 1917 for high‐level production of heparosan
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28315
Abstract: Heparosan is a crucial‐polysaccharide precursor for the chemoenzymatic synthesis of heparin, a widely used anticoagulant drug. Presently, heparosan is mainly extracted with the potential risk of contamination from Escherichia coli strain K5, a pathogenic bacterium… read more here.
Keywords: nissle 1917; chromosome evolution; escherichia coli; kps locus ... See more keywords
Effects of Escherichia coli strain Nissle 1917 on exercise-induced disruption of gastrointestinal integrity
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-020-04382-w
Abstract: The aim of the current study was to investigate the effects of the probiotic Escherichia coli strain Nissle 1917 (EcN) on the exercise-induced disruption of gastrointestinal (GI) integrity and the associated release of damage and… read more here.
Keywords: strain nissle; coli strain; escherichia coli; integrity ... See more keywords
Genome-wide identification of probiotic Escherichia coli Nissle 1917 (EcN) fitness genes during adhesion to the intestinal epithelial cells Caco-2.
Sign Up to like & getrecommendations! Published in 2021 at "Gene"
DOI: 10.1016/j.gene.2021.145890
Abstract: Escherichia coli Nissle 1917 (EcN) is an efficient probiotic strain extensively used worldwide because of its several health benefits. Adhesion to the intestinal cells is one of the prerequisites for a probiotic strain. To identify… read more here.
Keywords: escherichia coli; 1917 ecn; adhesion; coli nissle ... See more keywords
Improved Method for the Incorporation of Heme Cofactors into Recombinant Proteins Using Escherichia coli Nissle 1917.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00242
Abstract: Recombinant production of heme proteins in Escherichia coli is often limited by the availability of heme in the host. Therefore, several methods, including the reconstitution of heme proteins after production but prior to purification or… read more here.
Keywords: production; heme; escherichia coli; heme proteins ... See more keywords
Effects of Supernatants from Escherichia coli Nissle 1917 and Faecalibacterium prausnitzii on Intestinal Epithelial Cells and a Rat Model of 5-Fluorouracil-Induced Mucositis
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2017.1263747
Abstract: ABSTRACT Faecalibacterium prausnitzii (Fp) and Escherichia coli Nissle 1917 (EcN) are probiotics, which have been reported to ameliorate certain gastrointestinal disorders. We evaluated the effects of supernatants (SN) derived from Fp and EcN on 5-fluorouracil… read more here.
Keywords: effects supernatants; mucositis; faecalibacterium prausnitzii; escherichia coli ... See more keywords
Prospective and challenges of live bacterial therapeutics from a superhero Escherichia coli Nissle 1917.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in microbiology"
DOI: 10.1080/1040841x.2022.2109405
Abstract: Escherichia coli Nissle 1917 (EcN), the active component of Mutaflor(R), is a notable probiotic from Gram-negative to treat Crohn's disease and irritable bowel syndrome. Therefore, a comprehensive genomic database maximizes the systemic probiotic assessment to… read more here.
Keywords: engineered ecn; nissle 1917; coli nissle; escherichia coli ... See more keywords
Engineering a probiotic strain of Escherichia coli to induce the regression of colorectal cancer through production of 5‐aminolevulinic acid
Sign Up to like & getrecommendations! Published in 2021 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13894
Abstract: Bacterial vectors can be engineered to generate microscopic living therapeutics to produce and deliver anticancer agents. Escherichia coli Nissle 1917 (Nissle 1917) is a promising candidate with probiotic properties. Here, we used Nissle 1917 to… read more here.
Keywords: ala; escherichia coli; aminolevulinic acid; colorectal cancer ... See more keywords
Probiotic Escherichia coli Nissle 1917 inhibits bacterial persisters that survive fluoroquinolone treatment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15541
Abstract: Bacterial persisters are rare phenotypic variants in clonal bacterial cultures that can endure antimicrobial therapy and potentially contribute to infection relapse. Here, we investigate the potential of leveraging microbial interactions to disrupt persisters as they… read more here.
Keywords: nissle 1917; coli nissle; probiotic escherichia; escherichia coli ... See more keywords
Effect of Probiotic E. coli Nissle 1917 Supplementation on the Growth Performance, Immune Responses, Intestinal Morphology, and Gut Microbes of Campylobacter jejuni Infected Chickens
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00337-22
Abstract: Campylobacter jejuni is the most common cause of bacterial foodborne gastroenteritis and holds significant public health importance. The continuing increase of antibiotic-resistant Campylobacter necessitates the development of antibiotic-alternative approaches to control infections in poultry and… read more here.
Keywords: nissle 1917; coli nissle; campylobacter jejuni; immune responses ... See more keywords
A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917
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DOI: 10.1128/msphere.00624-21
Abstract: Nissle 1917 is sold as a probiotic and considered safe even though it has been known since 2006 that it harbors the genes for colibactin synthesis. Colibactin is a potent genotoxin that is now linked… read more here.
Keywords: genotoxin; nissle 1917; colibactin; escherichia coli ... See more keywords
Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008029
Abstract: Although Escherichia coli Nissle 1917 (EcN) has been used therapeutically for over a century, the determinants of its probiotic properties remain elusive. EcN produces two siderophore-microcins (Mcc) responsible for an antagonistic activity against other Enterobacteriaceae.… read more here.
Keywords: escherichia coli; coli nissle; ecn; antagonistic activity ... See more keywords