Quantitative Proteomics Based on iTRAQ Reveal that Nitidine Chloride Induces Apoptosis by Activating JNK/c-Jun Signaling in Hepatocellular Carcinoma Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Planta medica"
DOI: 10.1055/a-1676-4307
Abstract: The aim of the present study was to investigate the cytotoxic effects and underlying molecular mechanisms of nitidine chloride (NC) in hepatocellular carcinoma cells via quantitative proteomics. MTT assays were used to detect the inhibitory… read more here.
Keywords: jun; hepatocellular carcinoma; jnk; quantitative proteomics ... See more keywords
Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.919940
Abstract: Osteoarthritis (OA) is one of the most common chronic musculoskeletal disorder worldwide, representing a major source of disability, pain and socioeconomic burden. Yet the effective pharmaceutical treatments applied in the clinical works are merely symptomatic… read more here.
Keywords: scavenging ros; osteoarthritis; cellular senescence; nitidine chloride ... See more keywords