Vascular biotransformation of organic nitrates is independent of cytochrome P450 monooxygenases
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DOI: 10.1111/bph.15362
Abstract: Organic nitrates such as nitroglycerin (NTG) or pentaerythritol tetranitrate (PETN) have been used for over a century in the treatment of angina or ischaemic heart disease. These compounds are prodrugs which release their nitrovasodilators upon… read more here.
Keywords: vascular biotransformation; nitrates independent; independent cytochrome; cytochrome p450 ... See more keywords