Mechanochemical Assembly of a Nitrile‐Based Directing Group in Arylacetic AcidsUsing the Passerini 3‐CR: Exploration of the Pd(II)‐Catalyzed meta‐C(sp2)‐H Bond olefination Process
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DOI: 10.1002/ejoc.202301320
Abstract: The multicomponent assembly of a nitrile‐based directing group in a set of arylacetic acids under solvent‐free mechanochemical conditions using the Passerini 3‐CR and the subsequent Pd(II)‐mediated meta‐C(sp2)‐H bond olefination process has been achieved. The protocol… read more here.
Keywords: directing group; sp2 bond; based directing; nitrile based ... See more keywords