Dipeptidyl nitrile derivatives suppress the Trypanosoma cruzi in vitro infection.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2020.108032
Abstract: Chagas disease affects several countries around the world with health and sanitation problems. Cysteine proteases are essential for the virulence and replication of the Trypanosoma cruzi, being modulated by dipeptidyl nitriles and derivatives. Here, four… read more here.
Keywords: dipeptidyl nitrile; nitrile derivatives; cysteine proteases; cruzi ... See more keywords
Interaction of Some Amino-Nitrile Derivatives with Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) Using a Theoretical Model
Sign Up to like & getrecommendations! Published in 2023 at "Drug Research"
DOI: 10.1055/a-2062-3571
Abstract: Abstract Background Some studies indicate that the angiogenesis process is related to vascular endothelial growth factor, which can interact with endothelial cell surface receptors (VEGF-R1, VEGF-R2, and VEGF-R3); this biochemical process and other factors result… read more here.
Keywords: growth; amino; amino nitrile; interaction amino ... See more keywords