1,3-Dipolar Cycloaddition Reactions of Nitrile Oxides under "Non-Conventional" Conditions: Green Solvents, Irradiation, and Continuous Flow.
Sign Up to like & getrecommendations! Published in 2020 at "ChemPlusChem"
DOI: 10.1002/cplu.202000448
Abstract: The 1,3-dipolar cycloaddition reactions (DCs) of nitrile oxides (NOs) to alkenes and alkynes are useful methods for the synthesis of 2-isoxazolines and isoxazoles respectively, which are important classes of heterocyclic compounds in organic and medicinal… read more here.
Keywords: cycloaddition reactions; chemistry; nitrile oxides; reactions nitrile ... See more keywords
Synthesis of 1,2,4-Oxadiazolines through Deoxygenative Cyclization of N-Vinyl-α,β-Unsaturated Nitrones with in Situ Generated Nitrile Oxides from Hydroxamoyl Chlorides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04121
Abstract: A variety of 1,2,4-oxadiazoline derivatives were synthesized in moderate to good yields through a deoxygenative cyclization cascade reaction of N-vinyl-α,β-unsaturated nitrones and hydroxamoyl chlorides. Mechanistic studies revealed that the reaction underwent double additions of nitrile… read more here.
Keywords: deoxygenative cyclization; hydroxamoyl chlorides; unsaturated nitrones; vinyl unsaturated ... See more keywords
DABCO-mediated [3+3] cycloaddition of azomethine imines with in situ generated nitrile oxides from hydroximoyl chlorides.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc05367k
Abstract: A novel cross 1,3-dipolar cycloaddition between azomethine imines with in situ generated nitrile oxides has been developed. This is the first example of employing a reaction partner containing two heteroatoms in the [3+3] cycloaddition involving… read more here.
Keywords: nitrile oxides; azomethine imines; cycloaddition azomethine; imines situ ... See more keywords