Involvement of nitric oxide/reactive oxygen species signaling via 8-nitro-cGMP formation in 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells and rat cerebellar granule neurons.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.088
Abstract: To investigate the role of nitric oxide (NO)/reactive oxygen species (ROS) redox signaling in Parkinson's disease-like neurotoxicity, we used 1-methyl-4-phenylpyridinium (MPP+) treatment (a model of Parkinson's disease). We show that MPP+-induced neurotoxicity was dependent on… read more here.
Keywords: mpp; cells rat; induced neurotoxicity; neurotoxicity ... See more keywords
Reactive Persulfides from Salmonella Typhimurium Downregulate Autophagy-Mediated Innate Immunity in Macrophages by Inhibiting Electrophilic Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2018.08.007
Abstract: Reactive persulfides such as cysteine persulfide and glutathione persulfide are produced by bacteria including Salmonella during sulfur metabolism. The biological significance of bacterial reactive persulfides in host-pathogen interactions still warrants investigation. We found that reactive persulfides… read more here.
Keywords: salmonella typhimurium; autophagy mediated; inhibiting electrophilic; autophagy ... See more keywords
8-Nitro-cGMP suppresses mineralization by mouse osteoblasts
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.21-129
Abstract: Nitric oxide and reactive oxygen species regulate bone remodeling, which occurs via bone formation and resorption by osteoblasts and osteoclasts, respectively. Recently, we found that 8-nitro-cGMP, a second messenger of nitric oxide and reactive oxygen… read more here.
Keywords: nitro cgmp; cgmp; osteoblastic phenotypes; expression osteoblastic ... See more keywords