6-Nitro-4,7-dihydroazolo [1,5-a]pyrimidines: an alternative mechanism of formation and studies of alkylation
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DOI: 10.1007/s10593-020-02839-6
Abstract: The mechanism of a multicomponent reaction between aminoazoles, 1-morpholino-2-nitroalkenes, and benzaldehyde was studied in acidic medium. Performing the reaction in acetic acid led to the formation of 6-nitro-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]-pyrimidines, which subsequently underwent a rearrangement. Reaction conditions… read more here.
Keywords: nitro dihydroazolo; mechanism; alternative mechanism; dihydroazolo pyrimidines ... See more keywords
Methods of Synthesis and Antiviral Activity of New 4-Alkyl-3-Nitro-1,4-Dihydroazolo[5,1-c][1,2,4]Triazin-4-ols
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DOI: 10.1007/s10593-021-02926-2
Abstract: An azo coupling reaction of α-nitro ketones with 5-diazoazoles was used to obtain 4-alkyl-3-nitro-1,4-dihydroazolo[5,1- с ][1,2,4]triazines, which were characterized with respect to their antiviral activity against influenza and Coxsackie B3 viruses. read more here.
Keywords: antiviral activity; alkyl nitro; methods synthesis; nitro dihydroazolo ... See more keywords