Anti‐inflammatory nitro‐fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.06.014
Abstract: Graphical abstract Figure. No caption available. &NA; Nitro‐fatty acids (NFAs) are endogenously occurring lipid mediators exerting strong anti‐inflammatory effects and acting as anti‐oxidants in a number of animal models of inflammation. These NFA effects are… read more here.
Keywords: colorectal cancer; fatty acids; nitro fatty; crc ... See more keywords
Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.101987
Abstract: Psoriasis is a chronic inflammatory skin disease with no cure. Although the origin of psoriasis and its underlying pathophysiology remain incompletely understood, inflammation is a central mediator of disease progression. In this regard, electrophilic nitro-fatty… read more here.
Keywords: electrophilic nitro; psoriasiform; fatty acids; psoriasiform dermatitis ... See more keywords
Endogenous Biosynthesis of S-Nitrosoglutathione From Nitro-Fatty Acids in Plants
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00962
Abstract: Nitro-fatty acids (NO2-FAs) are novel molecules resulting from the interaction of unsaturated fatty acids and nitric oxide (NO) or NO-related molecules. In plants, it has recently been described that NO2-FAs trigger an antioxidant and a… read more here.
Keywords: biosynthesis; fatty acids; gsno; no2 fas ... See more keywords