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Published in 2017 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989017001177
Abstract: The title nitropyrrole-based compounds are intermediates used in the synthesis of modified DNA minor-groove binders. They are ethyl 4-nitro-1H-pyrrole-2-carboxylate, its derivative ethyl 4-nitro-1-(4-pentynyl)-1H-pyrrole-2-carboxylate, N-[3-(dimethylamino)propyl]-1-isopentyl-4-nitro-1H-pyrrole-2-carboxamide and 1-(3-azidopropyl)-4-(1-methyl-4-nitro-1H-pyrrole-2-carboxamido)-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide.
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Keywords:
pyrrole;
nitro pyrrole;
minor groove;
groove binders ... See more keywords