Gata-6 expression is decreased in diaphragmatic and pulmonary mesenchyme of fetal rats with nitrofen-induced congenital diaphragmatic hernia
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DOI: 10.1007/s00383-017-4219-8
Abstract: PurposeCongenital diaphragmatic hernia (CDH) and associated pulmonary hypoplasia are thought to be caused by a malformation of the underlying diaphragmatic and airway mesenchyme. GATA binding protein 6 (Gata-6) is a zinc finger-containing transcription factor that… read more here.
Keywords: gata; diaphragmatic hernia; nitrofen induced; gata expression ... See more keywords
Yes-associated protein is dysregulated during nitrofen-induced hypoplastic lung development due to congenital diaphragmatic hernia
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DOI: 10.1007/s00383-022-05099-x
Abstract: Congenital diaphragmatic hernia (CDH) is a birth defect associated with abnormal lung development. Yes-associated protein (YAP) is a core kinase of the Hippo pathway, which controls organ size during development. The absence of YAP protein… read more here.
Keywords: development; lung; lung development; yap ... See more keywords
Follistatin-like 1 expression is decreased in the alveolar epithelium of hypoplastic rat lungs with nitrofen-induced congenital diaphragmatic hernia.
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DOI: 10.1016/j.jpedsurg.2017.01.020
Abstract: BACKGROUND/PURPOSE Pulmonary hypoplasia (PH), characterized by incomplete alveolar development, remains a major therapeutic challenge associated with congenital diaphragmatic hernia (CDH). Follistatin-like 1 (Fstl1) is a crucial regulator of alveolar formation and maturation, which is strongly… read more here.
Keywords: congenital diaphragmatic; diaphragmatic hernia; nitrofen induced; alveolar epithelium ... See more keywords