Nitrogen-Centered Radicals in Functionalization of sp2 Systems: Generation, Reactivity, and Applications in Synthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.1c00831
Abstract: The chemistry of nitrogen-centered radicals (NCRs) has plentiful applications in organic synthesis, and they continue to expand as our understanding of these reactive species increases. The utility of these reactive intermediates is demonstrated in the… read more here.
Keywords: functionalization sp2; functionalization; synthesis; generation reactivity ... See more keywords
Nitrogen-Centered Concave Molecules with Double Fused Pentagons.
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DOI: 10.1021/acs.orglett.9b01861
Abstract: Distinctive concave compounds bearing a nitrogen core and double fused pentagons were synthesized with a palladium-catalyzed intramolecular coupling of 1-chloro-8 H-indolo[3,2,1- de]acridine as the key step. Structural analysis confirmed the formation of bowl-shaped molecules. Experimental… read more here.
Keywords: double fused; molecules double; nitrogen centered; fused pentagons ... See more keywords
Nitrogen-Centered Lactate Oxidase Nanozyme for Tumor Lactate Modulation and Microenvironment Remodeling.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c02005
Abstract: Designing nanozymes that match natural enzymes have always been an attractive and challenging goal. In general, researchers mainly focus on the construction of metal centers and the control of non-metallic ligands of nanozyme to regulate… read more here.
Keywords: microenvironment; lactate oxidase; lactate; nitrogen centered ... See more keywords