Azole and 5-nitroimidazole based nanoformulations are potential antiamoebic drug candidates against brain eating amoebae.
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DOI: 10.1093/jambio/lxad072
Abstract: AIM Herein, the anti-parasitic activity of azoles (fluconazole and itraconazole) and 5-nitroimdazole (metronidazole) against brain eating amoebae: Naegleria fowleri and Balamuthia mandrillaris was elucidated. METHODS AND RESULTS Azoles and 5-nitroimdazole based nanoformulations were synthesized and… read more here.
Keywords: azole nitroimidazole; based nanoformulations; brain eating; nitroimidazole based ... See more keywords