Design, synthesis and biological evaluation of novel N-nitrophenyl derivatives based on the structure of acetohydroxyacid synthase.
Sign Up to like & getrecommendations! Published in 2018 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2018.01.011
Abstract: Acetohydroxyacid synthase (AHAS, EC: 2.2.1.6) is a target for the development of novel herbicides. Two series of N-nitrophenyl derivatives, type-A and type-B, were designed and synthesized based on the active site of the AHAS structure.… read more here.
Keywords: acetohydroxyacid synthase; nitrophenyl derivatives; ahas enzyme; structure ... See more keywords
Quinazolinone-Peptido-Nitrophenyl-Derivatives as Potential Inhibitors of SARS-CoV-2 Main Protease
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15020287
Abstract: The severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2-Mpro) plays an essential role in viral replication, transcription, maturation, and entry into host cells. Furthermore, its cleavage specificity for viruses, but not humans, makes it… read more here.
Keywords: peptido nitrophenyl; main protease; quinazolinone peptido; nitrophenyl derivatives ... See more keywords