Alkylation of Nitropyridines via Vicarious Nucleophilic Substitution
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DOI: 10.1021/acs.orglett.1c03920
Abstract: Electrophilic nitropyridines react with sulfonyl-stabilized carbanions to give products of C–H alkylation via vicarious nucleophilic substitution. The process consists of formation of the Meisenheimer-type adduct followed by base-induced β-elimination of the sulfinic acid (e.g., PhSO2H).… read more here.
Keywords: nitropyridines via; vicarious nucleophilic; via vicarious; alkylation nitropyridines ... See more keywords