Hemicyanine‐Based Highly Water‐Soluble Probe for Extracellular Nitroreductase
Sign Up to like & getrecommendations! Published in 2024 at "ChemBioChem"
DOI: 10.1002/cbic.202400257
Abstract: Nitroreductase (NTR) has long been a target of interest for its important role involved in the nitro compounds metabolism. Various probes have been reported for NTR analysis, but rarely able to distinguish the extracellular NTR… read more here.
Keywords: hemicyanine; nitro group; group; probe extracellular ... See more keywords
Diagnosis of Bacterial Plant Diseases via a Nitroreductase-Activated Fluorescent Sensor.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04614
Abstract: Plant diseases caused by bacteria have become one of the serious problems that threaten human food security, which led to the remarkable reduction of agricultural yields and economic loss. Nitroreductase (NTR), as an important biomarker,… read more here.
Keywords: fluorescent sensor; diagnosis; plant; plant diseases ... See more keywords
Harnessing the Potential of a Nitroreductase-Responsive Fluorescent Probe for the Diagnosis of Bacterial Keratitis.
Sign Up to like & getrecommendations! Published in 2024 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.4c00234
Abstract: Bacterial keratitis, an ocular emergency, is the predominant cause of infectious keratitis. However, diagnostic procedures for it are invasive, time-consuming, and expeditious, thereby limiting effective treatment for the disease in the clinic. It is imperative… read more here.
Keywords: diagnosis bacterial; bacterial keratitis; keratitis; probe ... See more keywords
Supramolecular Host-Guest Strategy for the Accelerating Detection of Nitroreductase.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c22851
Abstract: Identifying nitroreductase (NTR) with fluorescent techniques has become a research hotspot, due to its good sensitivity and selectivity toward the early-stage cancer diagnosis and monitoring. Herein, a host-guest reporter (NAQA⊂Zn-MPPB) is successfully achieved by encapsulating… read more here.
Keywords: host; host guest; guest strategy; nitroreductase ... See more keywords
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.7b00111
Abstract: The success of Mycobacterium tuberculosis (Mtb) as a pathogen depends on the redundant and complex mechanisms it has evolved for resisting nitrosative and oxidative stresses inflicted by host immunity. Improving our understanding of these defense… read more here.
Keywords: mycothiol dependent; nitroreductase; dependent nitroreductase; mycobacterium tuberculosis ... See more keywords
Nitroreductase-Responsive Fluorescent “Off-On” Photosensitizer for Hypoxic Tumor Imaging and Dual-Modal Therapy
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c03098
Abstract: Photothermal therapy synergized with photodynamic therapy for the treatment of tumors has emerged as a promising strategy. However, designing photosensitizers with both high photothermal efficiency and high photodynamic performance remains challenging. In contrast, the strategy… read more here.
Keywords: photothermal therapy; energy; therapy; photosensitizer ... See more keywords
Sensitive imaging of tumors using a nitroreductase-activated fluorescence probe in the NIR-II window.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc03232a
Abstract: A nitroreductase (NTR)-activated NIR-II fluorescence probe for tumor imaging is reported. The probe can emit fluorescence in the range of 900-1300 nm, and target hypoxic tumors with NTR overexpression, thus allowing for accurate delineation of… read more here.
Keywords: fluorescence; sensitive imaging; nitroreductase; fluorescence probe ... See more keywords