Synthetic Approach to the Natural N-Nitrosohydroxylamino Tetramic Acid JBIR-141.
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DOI: 10.1021/acs.orglett.2c02006
Abstract: An analogue of the Streptomyces metabolite JBIR-141, featuring a delicate N-nitrosohydroxylamine, a 3-acyltetramic acid, and an oxazoline, was synthesized by a convergent strategy from l-alanine, l-threonine, and l-glutamic acid. Key steps were the cyclization of… read more here.
Keywords: jbir 141; synthetic approach; natural nitrosohydroxylamino; nitrosohydroxylamino tetramic ... See more keywords