Iron-sulfur [2Fe-2S] nitrosyl complexes as new trend in synthesis of donors of nitric oxide for anti-aging therapy
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.073
Abstract: Aging is associated with dysfunctions in vascular smooth muscle cells, neurotransmission, renal and immune systems, to name just a few, many of which stems from decline in reliability of the regulatory functions of nitric oxide… read more here.
Keywords: medicine; nitrosyl complexes; iron sulfur; nitrosyl ... See more keywords
Blue-to-red light triggered nitric oxide release in cytotoxic/cytostatic ruthenium nitrosyl complexes bearing biomimetic ligands
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Photochemistry and Photobiology A: Chemistry"
DOI: 10.1016/j.jphotochem.2021.113520
Abstract: Abstract The nitrosyl complexes trans(L,L)-[RuNO(L)2Cl3] (L = indazole (I) and imidazole (II)) were synthesized and comprehensively characterized including by single crystal X-ray diffraction. Both compounds exhibit light-induced NO release under blue or green light (445,… read more here.
Keywords: ruthenium; nitrosyl complexes; cytotoxic; light ... See more keywords
Photorelease of nitric oxide (NO) on ruthenium nitrosyl complexes with phenyl substituted terpyridines
Sign Up to like & getrecommendations! Published in 2017 at "New Journal of Chemistry"
DOI: 10.1039/c7nj00866j
Abstract: We investigated the influence of the nature of the substituent on the 4′-position of terpyridine ligands and the geometry around the metal ion on the photosensitization of ruthenium nitrosyl complexes. This was achieved by synthesizing… read more here.
Keywords: phtpy cl2; nitrosyl complexes; ruthenium nitrosyl;
Ruthenium-nitrosyl complexes as NO-releasing molecules, potential anticancer drugs, and photoswitches based on linkage isomerism.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt00290f
Abstract: The synthesis of new types of mono- and polynuclear ruthenium nitrosyl complexes is driving progress in the field of NO generation for a variety of applications. Light-induced Ru-NO bond dissociation in solution may involve transient… read more here.
Keywords: potential anticancer; nitrosyl complexes; ruthenium nitrosyl; anticancer drugs ... See more keywords
Effects of Laser Radiation on Mitochondria and Mitochondrial Proteins Subjected to Nitric Oxide
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2018.00112
Abstract: The biological roles of heme and nonheme nitrosyl complexes in physiological and pathophysiological conditions as metabolic key players are considered in this study. Two main physiological functions of protein nitrosyl complexes are discussed—(1) a depot… read more here.
Keywords: nitrosyl complexes; protein nitrosyl; nitric oxide; activity ... See more keywords