LAUSR

NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism

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0 Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-01563-8

Abstract: Transcription factor MEF2C regulates multiple genes linked to autism spectrum disorder (ASD), and human MEF2C haploinsufficiency results in ASD, intellectual disability, and epilepsy. However, molecular mechanisms underlying MEF2C haploinsufficiency syndrome remain poorly understood. Here we… read more here.

Keywords: nitrosynapsin therapy; autism; haploinsufficiency; therapy mouse ... See more keywords