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Published in 2018 at "Endocrinology"
DOI: 10.1210/en.2018-00443
Abstract: Despite the well-established concept that an increase in pulsatile GnRH release triggers puberty, the precise signaling mechanism responsible for the pubertal increase in GnRH release remains unclear. A recent study indicates that developmental changes in…
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Keywords:
male rhesus;
kisspeptin neurokinin;
nkb signaling;
role ... See more keywords
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Published in 2018 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2018.00148
Abstract: In human patients, loss-of-function mutations in the genes encoding kisspeptin (KISS1) and neurokinin B (NKB) and their receptors (KISS1R and NK3R, respectively) result in an abnormal timing of puberty or the absence of puberty. To…
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Keywords:
nkb signaling;
kisspeptin;
gnrh release;
puberty ... See more keywords