Articles with "nkg2a blocking" as a keyword



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Abstract LB220: S095029: a novel clinical-stage Fc-silenced NKG2A-blocking antibody with best-in-class potential

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-lb220

Abstract: NKG2A and its ligand HLA-E are increasingly recognized as an important immune checkpoint restraining multiple lymphocyte populations involved in cancer immunity. Initially described as an NK cell inhibitory receptor, NKG2A’s role in regulating T-cell functions… read more here.

Keywords: nkg2a blocking; blocking antibody; s095029; clinical stage ... See more keywords