NKL homeobox gene activities in normal and malignant myeloid cells
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0226212
Abstract: Recently, we have documented a hematopoietic NKL-code mapping physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis, which spotlights genes deregulated in lymphoid malignancies. Here, we enlarge this map to include… read more here.
Keywords: homeobox genes; homeobox; nkl homeobox; homeobox gene ... See more keywords
NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma
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DOI: 10.18632/oncotarget.26459
Abstract: NKL homeobox genes encode basic transcriptional regulators of cell and tissue differentiation. Recently, we described a hematopoietic NKL-code comprising nine specific NKL homeobox genes expressed in normal hematopoietic stem cells, lymphoid progenitors and during lymphopoiesis,… read more here.
Keywords: gene nkx2; nkl homeobox; hodgkin lymphoma; homeobox ... See more keywords
Deregulated NKL Homeobox Genes in B-Cell Lymphoma
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DOI: 10.3390/cancers11121874
Abstract: Recently, we have described physiological expression patterns of NKL homeobox genes in early hematopoiesis and in subsequent lymphopoiesis. We identified nine genes which constitute the so-called NKL-code. Aberrant overexpression of code-members or ectopically activated non-code… read more here.
Keywords: nkl homeobox; deregulated nkl; homeobox genes; genes cell ... See more keywords
NKL Homeobox Genes NKX2-3 and NKX2-4 Deregulate Megakaryocytic-Erythroid Cell Differentiation in AML
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DOI: 10.3390/ijms222111434
Abstract: NKL homeobox genes encode transcription factors that impact normal development and hematopoietic malignancies if deregulated. Recently, we established an NKL-code that describes the physiological expression pattern of eleven NKL homeobox genes in the course of… read more here.
Keywords: genes nkx2; nkl homeobox; homeobox genes; expression ... See more keywords