Diminished natural killer T-like cells correlates with aggravated primary Sjögren’s syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-06011-z
Abstract: To reveal the characteristics and potential role of natural killer T-like cells (NKT-like cells) in the pathogenesis of primary Sjögren’s syndrome (pSS). Forty-six patients with pSS and 30 healthy subjects were enrolled in the study.… read more here.
Keywords: nkt like; natural killer; like cells; gren syndrome ... See more keywords
NK and NKT-like cells in granulomatous and fibrotic lung diseases
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-019-00578-3
Abstract: Background The pathogenetic and regulatory roles of natural killer (NK) and natural killer T-like cells in interstitial lung diseases (ILDs), fibrotic and granulomatous of unknown etiology are unclear. Objectives Here we investigated NK and NKT-like… read more here.
Keywords: cells granulomatous; like cells; nkt like; sarcoidosis ... See more keywords
Human CD3+CD56+NKT-like cells express a range of complement receptors and C3 activation has negative effects on these cell activity and effector function.
Sign Up to like & getrecommendations! Published in 2021 at "Human immunology"
DOI: 10.1016/j.humimm.2021.06.001
Abstract: CD3+CD56+NKT-like cells are a rare population of lymphocytes that serve important roles in various types of immune-related diseases, and particularly in cancer. The complement system regulates inflammatory and immune responses by interacting with complement receptors… read more here.
Keywords: cd3 cd56; like cells; cd56 nkt; nkt like ... See more keywords
Immune cell composition in the endometrium of patients with a complete molar pregnancy: Effects on outcome.
Sign Up to like & getrecommendations! Published in 2020 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2020.11.005
Abstract: OBJECTIVE In 15% of patients with complete hydatidiform mole (CHM), disease progresses to post-molar gestational trophoblastic neoplasia (GTN) after curettage. Tumor infiltrating lymphocytes (TILs) are essential in overcoming disease in many tumors. Infiltrating lymphocyte composition… read more here.
Keywords: patients chm; gtn; density; nkt like ... See more keywords
Altered phenotypic and metabolic characteristics of FOXP3+CD3+CD56+ natural killer T (NKT)-like cells in human malignant pleural effusion
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2160558
Abstract: ABSTRACT Malignant pleural effusion (MPE) is a functional ‘cold’ tumor microenvironment in which the antitumor activity of CD8+ T cells and natural killer T (NKT)-like cells is suppressed and the function of regulatory T (Treg)… read more here.
Keywords: pleural effusion; malignant pleural; nkt like; natural killer ... See more keywords
BOS Is Associated With Decreased SIRT1 in Peripheral Blood Proinflammatory T, NK, and NKT-like Lymphocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002817
Abstract: BACKGROUND Immunosuppression therapy is ineffective at preventing chronic rejection of lung allografts (bronchiolitis obliterans syndrome [BOS]) and proinflammatory cytokines by steroid-resistant lymphocytes. The class III NAD-sirtuin 1 (SIRT1) is an important negative regulator of inflammation;… read more here.
Keywords: blood; proinflammatory; lung transplant; nkt like ... See more keywords
Histone deacetylase 2 is decreased in peripheral blood pro‐inflammatory CD8+ T and NKT‐like lymphocytes following lung transplant
Sign Up to like & getrecommendations! Published in 2017 at "Respirology"
DOI: 10.1111/resp.12933
Abstract: Immunosuppression therapy following lung transplantation fails to prevent chronic rejection in many patients, which is associated with lack of suppression of cytotoxic mediators and pro‐inflammatory cytokines in peripheral blood T and natural killer T (NKT)‐like… read more here.
Keywords: following lung; nkt like; peripheral blood; lung transplant ... See more keywords
Spatial Organization and Prognostic Significance of NK and NKT-like Cells via Multimarker Analysis of the Colorectal Cancer Microenvironment
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-21-0772
Abstract: The authors develop a multiplex imaging protocol for quantifying lymphocyte populations in human colorectal cancer tissue. Cytotoxic NK and NKT-like cells are rare populations within the tumor microenvironment and show distinct spatial configuration and associations… read more here.
Keywords: like cells; ncam1 cd3; tumor; nkt like ... See more keywords
Diminished Frequency of Menstrual and Peripheral Blood NKT-Like Cells in Patients With Unexplained Recurrent Spontaneous Abortion and Infertile Women
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive Sciences"
DOI: 10.1177/1933719118766261
Abstract: Systemic monitoring of immune system may not precisely outline the local immune status in the uterus. This survey is a continuation of our previous studies on potential usefulness of menstrual blood (MB) immunophenotyping as a… read more here.
Keywords: frequency; like cells; unexplained recurrent; nkt like ... See more keywords
Cytotoxic lymphocytes in COPD airways: increased NK cells associated with disease, iNKT and NKT-like cells with current smoking
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Research"
DOI: 10.1186/s12931-018-0940-7
Abstract: BackgroundCytotoxic lymphocytes are increased in the airways of COPD patients. Whether this increase is driven primarily by the disease or by smoking is not clear, nor whether it correlates with the rate of decline in… read more here.
Keywords: current smoking; like cells; nkt like; copd ... See more keywords
NKT-Like (CD3+CD56+) Cells in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02493
Abstract: Therapy with Tyrosine Kinase Inhibitors (TKI) aiming stable deep molecular response is the gold standard to treat Chronic Myeloid Leukemia (CML). NKT-like cells (CD3+CD56+) combine characteristics of T and NK cells. The physiopathological role of… read more here.
Keywords: cml patients; kinase inhibitors; like cells; nkt like ... See more keywords