Abstract 207: Tumor suppressive role of NKX2-1 in advanced thyroid cancer progression
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-207
Abstract: NKX2-1 is a homeodomain transcription factor, known as a master regulator of thyroid development. NKX2-1 is also crucial for lung epithelium differentiation, and the involvement of NKX2-1 in lung carcinogenesis and cancer progression has been… read more here.
Keywords: cancer; cancer progression; thyroid cancer; nkx2 ... See more keywords
Deciphering an isolated lung phenotype of NKX2-1 frameshift pathogenic variant
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.978598
Abstract: Background to perform a functional analysis of a new NK2 homeobox 1 (NKX2-1) variant (c.85_86del denominated NKX2-1DEL) identified in a family presenting with isolated respiratory disease, in comparison to another frameshift variant (c.254dup denominated NKX2-1DUP)… read more here.
Keywords: frameshift; microscopy; lung; nkx2 ... See more keywords
Mutational Assessment in NKX2-5 and ACTC1 Genes in Patients with Congenital Cardiac Septal Defect (CCSD) from Ethnic Kashmiri Population
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19169884
Abstract: (1) Background globe. The etiology of CHDs is complex and involves both genetic and non-genetic factors. Although, significant progress has been made in deciphering the genetic components involved in CHDs, recent reports have revealed that… read more here.
Keywords: ethnic kashmiri; etiology; kashmiri population; nkx2 ... See more keywords