Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements.
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DOI: 10.1016/j.ydbio.2020.07.003
Abstract: The sinoatrial node (SAN) is the primary pacemaker in the heart. During cardiogenesis, Shox2 and Nkx2-5 are co-expressed in the junction domain of the SAN and regulate pacemaker cell fate through a Shox2-Nkx2-5 antagonism. Cx40… read more here.
Keywords: nkx2 shox2; myocardial specific; specific transcription; gja5 ... See more keywords