Dynamic bidirectional regulation of NLRC3 and gammaherpesviruses during viral latency in B lymphocytes
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DOI: 10.1002/jmv.29504
Abstract: While most NOD‐like receptors (NLRs) are predominately expressed by innate immune cells, NLRC3, an inhibitory NLR of immune signaling, exhibits the highest expression in lymphocytes. The role of NLRC3 or any NLRs in B lymphocytes… read more here.
Keywords: regulation nlrc3; nlrc3; dynamic bidirectional; latency ... See more keywords
NLRC3 attenuates osteoclastogenesis by limiting TNFα+ Th17 cell response in osteoporosis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-024-02422-y
Abstract: NOD-like receptor family CARD domain containing 3 (NLRC3) is the intracellular protein belonging to NLR (NOD-like receptor) family. NLRC3 can negatively regulate inflammatory signal transduction pathways within the adaptive and innate immunocytes. However, studies need… read more here.
Keywords: bone; tnf th17; th17 cell; nlrc3 ... See more keywords