LAUSR

NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses

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1 Published in 2021 at "iScience"

DOI: 10.1016/j.isci.2021.102548

Abstract: Summary The recognition of fungi by intracellular NOD-like receptors (NLRs) induces inflammasome assembly and activation. Although the NLRC4 inflammasome has been extensively studied in bacterial infections, its role during fungal infections is unclear. Paracoccidioidomycosis (PCM)… read more here.

Keywords: cell responses; cd8; inhibits nlrp3; nlrp3 inflammasome ... See more keywords