Articles with "nlrp3 aim2" as a keyword



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Chrysanthemum indicum extract inhibits NLRP3 and AIM2 inflammasome activation via regulating ASC phosphorylation.

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Published in 2019 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2019.111917

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Chrysanthemum indicum (C. indicum), a perennial plant, has long been used to treat inflammation-related disorders, such as pneumonia, hypertension, gastritis, and gastroenteritis. AIM OF THE STUDY The inhibitory effect of C. indicum extract… read more here.

Keywords: inflammasome activation; indicum extract; msu induced; nlrp3 aim2 ... See more keywords
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SOCS3 protects against neonatal necrotizing enterocolitis via suppressing NLRP3 and AIM2 inflammasome activation and p65 nuclear translocation.

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Published in 2020 at "Molecular immunology"

DOI: 10.1016/j.molimm.2020.03.019

Abstract: BACKGROUND Necrotizing enterocolitis (NEC) is an acquired disorder of mucosal damage characterized by the diffuse or local necrosis of the intestine. The suppressor of cytokine signaling 3 (SOCS3) has been demonstrated to possess anti-inflammatory action… read more here.

Keywords: aim2 inflammasome; socs3; p65 nuclear; nlrp3 aim2 ... See more keywords
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Activation of the NLRP3 and AIM2 inflammasomes in a mouse model of Schistosoma mansoni infection.

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Published in 2019 at "Journal of helminthology"

DOI: 10.1017/s0022149x19000622

Abstract: Schistosomiasis is an inflammatory disease that occurs when schistosome species eggs are deposited in the liver, resulting in fibrosis and portal hypertension. Schistosomes can interact with host inflammasomes to elicit host immune responses, leading to… read more here.

Keywords: activation; activation nlrp3; mansoni infection; schistosoma mansoni ... See more keywords
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The Role of NLRP1, NLRP3, and AIM2 Inflammasomes in Psoriasis: Review

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22115898

Abstract: Inflammasomes are high-molecular-weight protein complexes that may cleave the two main proinflammatory cytokines, pro-interleukin-1β and pro-interleukin-18, into active forms, and contribute to psoriasis. Despite recent advances made in the pathogenesis of psoriasis, mainly studied as… read more here.

Keywords: nlrp1 nlrp3; nlrp3 aim2; psoriasis; pathogenesis psoriasis ... See more keywords
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The P2X7R-NLRP3 and AIM2 Inflammasome Platforms Mark the Complexity/Severity of Viral or Metabolic Liver Damage

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23137447

Abstract: P2X7R-NLRP3 and AIM2 inflammasomes activate caspase-1 and the release of cytokines involved in viral-related liver disease. Little is known about their role in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steato-hepatitis (NASH). We characterized the… read more here.

Keywords: p2x7r nlrp3; expression; hcv; aim2 inflammasome ... See more keywords