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Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.111917
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Chrysanthemum indicum (C. indicum), a perennial plant, has long been used to treat inflammation-related disorders, such as pneumonia, hypertension, gastritis, and gastroenteritis. AIM OF THE STUDY The inhibitory effect of C. indicum extract…
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Keywords:
inflammasome activation;
indicum extract;
msu induced;
nlrp3 aim2 ... See more keywords
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Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.03.019
Abstract: BACKGROUND Necrotizing enterocolitis (NEC) is an acquired disorder of mucosal damage characterized by the diffuse or local necrosis of the intestine. The suppressor of cytokine signaling 3 (SOCS3) has been demonstrated to possess anti-inflammatory action…
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Keywords:
aim2 inflammasome;
socs3;
p65 nuclear;
nlrp3 aim2 ... See more keywords
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Published in 2019 at "Journal of helminthology"
DOI: 10.1017/s0022149x19000622
Abstract: Schistosomiasis is an inflammatory disease that occurs when schistosome species eggs are deposited in the liver, resulting in fibrosis and portal hypertension. Schistosomes can interact with host inflammasomes to elicit host immune responses, leading to…
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Keywords:
activation;
activation nlrp3;
mansoni infection;
schistosoma mansoni ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22115898
Abstract: Inflammasomes are high-molecular-weight protein complexes that may cleave the two main proinflammatory cytokines, pro-interleukin-1β and pro-interleukin-18, into active forms, and contribute to psoriasis. Despite recent advances made in the pathogenesis of psoriasis, mainly studied as…
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Keywords:
nlrp1 nlrp3;
nlrp3 aim2;
psoriasis;
pathogenesis psoriasis ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137447
Abstract: P2X7R-NLRP3 and AIM2 inflammasomes activate caspase-1 and the release of cytokines involved in viral-related liver disease. Little is known about their role in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steato-hepatitis (NASH). We characterized the…
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Keywords:
p2x7r nlrp3;
expression;
hcv;
aim2 inflammasome ... See more keywords