Articles with "nlrp3 deacetylation" as a keyword



LARP7 protects against ischemic brain injury by modulating NLRP3 deacetylation to suppress neuronal pyroptosis.

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Published in 2025 at "Journal of neuroinflammation"

DOI: 10.1186/s12974-025-03649-3

Abstract: Ischemic stroke is a leading cause of morbidity and mortality worldwide, yet available therapeutic strategies remain limited. La ribonucleoprotein domain family member 7 (LARP7), a critical regulator of RNA stability and transcriptional control, participates in… read more here.

Keywords: nlrp3 deacetylation; neuronal pyroptosis; larp7; ischemic stroke ... See more keywords