PKR induces the expression of NLRP3 by regulating the NF‐&kgr;B pathway in Porphyromonas gingivalis‐infected osteoblasts
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.03.028
Abstract: ABSTRACT The double‐stranded RNA‐dependent kinase (PKR), which is activated by double stranded RNA, induces inflammation by regulating NF‐&kgr;B signaling. The NLR family pyrin domain‐containing 3 (NLRP3) inflammasome also modulates inflammation in response to infection. Porphyromonas… read more here.
Keywords: expression nlrp3; inflammation; gingivalis; expression ... See more keywords
HBx promotes podocyte-macrophage transdifferentiation by mediating NLRP3 expression in hepatitis B virus-associated glomerulonephritis
Sign Up to like & getrecommendations! Published in 2025 at "Virology Journal"
DOI: 10.1186/s12985-025-02926-0
Abstract: Podocytes are identified as main injury targets in the pathogenesis of hepatitis B virus (HBV)-associated glomerulonephritis (HBV-GN). NLR family pyrin domain containing 3 (NLRP3) has a critical function in inducing podocyte injury across multiple renal… read more here.
Keywords: podocyte macrophage; hepatitis virus; associated glomerulonephritis; nlrp3 expression ... See more keywords