Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization.
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DOI: 10.1016/j.molimm.2021.03.025
Abstract: Brevilin A (BA), is a natural biologically active ingredient derived from Centipeda minima with several reports of anti-cancer, while its anti-inflammatory activity is rarely reported. Current studies have found the dysregulated activation of NLRP3 inflammasome… read more here.
Keywords: inflammasome activation; nlrp3 induced; inhibits nlrp3; activation ... See more keywords