Endogenous innate sensor NLRP3 is a key component in peritoneal macrophage dynamics required for cestode establishment
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DOI: 10.1007/s12026-024-09496-3
Abstract: The NLRP3 receptor can assemble inflammasome platforms to trigger inflammatory responses; however, accumulating evidence suggests that it can also display anti-inflammatory properties. Here, we explored the role of nucleotide-binding oligomerization domain pyrin-containing protein 3 (NLRP3)… read more here.
Keywords: mice; macrophage; endogenous innate; nlrp3 mice ... See more keywords
Rhabdomyolysis-Induced AKI Was Ameliorated in NLRP3 KO Mice via Alleviation of Mitochondrial Lipid Peroxidation in Renal Tubular Cells
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DOI: 10.3390/ijms21228564
Abstract: Introduction: A recent study showed that early renal tubular injury is ameliorated in Nod-like receptor pyrin domain-containing protein 3 (NLRP3) KO mice with rhabdomyolysis-induced acute kidney injury (RIAKI). However, the precise mechanism has not been… read more here.
Keywords: lipid peroxidation; renal tubular; mice; nlrp3 mice ... See more keywords