Increased levels of NLRP3 in children with febrile seizures
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Development"
DOI: 10.1016/j.braindev.2019.12.013
Abstract: OBJECTIVE Febrile seizures (FS) are the most common convulsions in childhood. Interleukin-1beta (IL-1β) is proposed to play an important role in the development of FS, from in vitro data and data from peripheral blood samples.… read more here.
Keywords: fever controls; increased levels; nlrp3 protein; children febrile ... See more keywords
A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of pharmacology"
DOI: 10.1111/bph.16058
Abstract: BACKGROUND AND PURPOSE Chronic inflammation is pathogenic and contributes to many human diseases, positing a significant threat to the public health. The NLR family pyrin domain-containing protein 3 (NLRP3) is the best-characterized factor regulating inflammation.… read more here.
Keywords: inflammation; compound; nlrp3 protein; degradation ... See more keywords
NLRP3 inflammasome activation contributes to the cognitive decline after cardiac surgery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.992769
Abstract: Background Perioperative neurocognitive disorders (PND) are a common complication of cardiac surgery in elderly patients. The etiopathogenesis of PND is not clear. Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, a macromolecular protein complex,… read more here.
Keywords: nlrp3 protein; surgery; cardiac surgery; serum nlrp3 ... See more keywords