Intracerebroventricular Injection of the Glutamatergic Receptors Antagonist Affects N/OFQ-Induced Hyperphagia in Neonatal Broilers: Role of NMDA and AMPA Receptors
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DOI: 10.1007/s10989-018-9733-6
Abstract: This study was designed to determine possible interaction of the central nociceptin/orphanin FQ (N/OFQ) and glutamatergic system on feeding behavior in neonatal broilers chicken. In experiment 1, 3-h food deprived (FD3) chicks received intracerebroventricular (ICV)… read more here.
Keywords: neonatal broilers; ofq induced; nmda ampa; injection ... See more keywords
Sip-1 mutations cause disturbances in the activity of NMDA- and AMPA-, but not kainate receptors of neurons in the cerebral cortex
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DOI: 10.1016/j.neulet.2017.04.048
Abstract: Smad-interacting protein-1 (Sip1) [Zinc finger homeobox (Zfhx1b), Zeb2] is a transcription factor implicated in the genesis of Mowat-Wilson syndrome (MWS) in humans. MWS is a rare genetic autosomal dominant disease caused by a mutation in… read more here.
Keywords: sip1; ampa; nmda ampa; mutations cause ... See more keywords
Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses
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DOI: 10.1016/j.neuron.2019.03.032
Abstract: AMPA- and NMDA-type glutamate receptors mediate distinct postsynaptic signals that differ characteristically among synapses. How postsynaptic AMPA- and NMDA-receptor levels are regulated, however, remains unclear. Using newly generated conditional knockin mice that enable genetic control… read more here.
Keywords: neurexin; ampa receptor; nmda ampa; receptor ... See more keywords
Role of NMDA and AMPA glutamatergic receptors in the effects of social defeat on the rewarding properties of MDMA in mice
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DOI: 10.1111/ejn.14190
Abstract: Exposure to social stress alters the response to drugs of abuse of experimental animals. Changes in the glutamatergic system seem to play a role in the effects of social defeat stress on the rewarding properties… read more here.
Keywords: social defeat; nmda ampa; effects social; rewarding properties ... See more keywords
NMDA and AMPA Receptors at Synapses: Novel Targets for Tau and α-Synuclein Proteinopathies
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DOI: 10.3390/biomedicines10071550
Abstract: A prominent feature of neurodegenerative diseases is synaptic dysfunction and spine loss as early signs of neurodegeneration. In this context, accumulation of misfolded proteins has been identified as one of the most common causes driving… read more here.
Keywords: misfolded proteins; ampa receptors; synapses novel; tau synuclein ... See more keywords