Hypothermia but not NMDA receptor antagonism protects against stroke induced by distal middle cerebral arterial occlusion in mice
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DOI: 10.1371/journal.pone.0229499
Abstract: Excitotoxicity mediated by the N-methyl-D-aspartate receptor (NMDAR) is believed to be a primary mechanism of neuronal injury following stroke. Thus, many drugs and therapeutic peptides were developed to inhibit either the NMDAR at the cell… read more here.
Keywords: middle cerebral; nmdar antagonism; cerebral arterial; model ... See more keywords