NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2017.11.002
Abstract: Research on the biology of NAD+ has been gaining momentum, providing many critical insights into the pathogenesis of age-associated functional decline and diseases. In particular, two key NAD+ intermediates, nicotinamide riboside (NR) and nicotinamide mononucleotide… read more here.
Keywords: nmn; biology therapeutic; nad intermediates; biology ... See more keywords
The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila
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DOI: 10.1101/2022.01.30.478002
Abstract: Axon degeneration contributes to the disruption of neuronal circuit function in diseased and injured nervous systems. Severed axons degenerate following the activation of an evolutionarily conserved signaling pathway, which culminates in the activation of SARM1… read more here.
Keywords: nad precursor; degeneration; axon degeneration; nmn ... See more keywords