Efficient NMR Screening Approach to Discover Small Molecule Fragments Binding Structured RNA.
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DOI: 10.1021/acsmedchemlett.1c00109
Abstract: We describe a scalable nuclear magnetic resonance (NMR) screening approach to identify and prioritize small molecule fragments that bind to structured RNAs. This approach is target agnostic and, therefore, amenable to many RNA structures and… read more here.
Keywords: screening approach; small molecule; approach; nmr screening ... See more keywords