Abstract 2545: NNMT is a novel effector of EGFR driven glioblastoma malignancy
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DOI: 10.1158/1538-7445.am2023-2545
Abstract: Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that catalyzes the conversion of methyl groups from S-adenosyl-L-methionine (SAM) to nicotinamide (NAM) to generate S-adenosine hyperblastoids (SAH) and 1-methylnicotinamide (MNA). Upregulation of NNMT has been observed in… read more here.
Keywords: glioblastoma; driven glioblastoma; nnmt novel; egfr driven ... See more keywords