E74-like factor 1 contributes to nerve trauma-induced nociceptive hypersensitivity via transcriptionally activating matrix metalloprotein-9 in dorsal root ganglion neurons.
Sign Up to like & getrecommendations! Published in 2022 at "Pain"
DOI: 10.1097/j.pain.0000000000002673
Abstract: ABSTRACT Nerve trauma-induced alternations of gene expression in the neurons of dorsal root ganglion (DRG) participate in nerve trauma-caused nociceptive hypersensitivity. Transcription factors regulate gene expression. Whether the transcription factor E74-like factor 1 (ELF1in the… read more here.
Keywords: factor; nociceptive hypersensitivity; nerve trauma; trauma ... See more keywords
Mechanical stimulation simulating osteopathic pressing manipulation inhibits nociceptive hypersensitivity and synovial inflammation in knee osteoarthritis rats by modulating trafficking dynamics of transient receptor potentials via complexin2
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DOI: 10.1186/s13018-025-06414-7
Abstract: Nociceptive hypersensitivity and synovial inflammation promote the progression of knee osteoarthritis (KOA) and joint pain, yet effective therapeutic strategies remain limited. This study investigated the mechanism of osteopathic pressing manipulation (OPM), a traditional Chinese spinal… read more here.
Keywords: nociceptive hypersensitivity; knee osteoarthritis; trafficking dynamics; synovial inflammation ... See more keywords